NCT03212898
Completed
Not Applicable
The Influence of Pharmacist Interventions on the Effectiveness of Warfarin Treatment in Elderly Patients From Rural Areas
Slaven Falamić0 sites131 target enrollmentMay 2015
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Atrial Fibrillation
- Sponsor
- Slaven Falamić
- Enrollment
- 131
- Primary Endpoint
- Time in therapeutic range (TTR)
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The primary study goal is to explore the influence of pharmacist interventions on the effectiveness of warfarin treatment in a specific subpopulation.
Investigators
Slaven Falamić
Slaven Falamić,MPharm, Prinicipal-Investigator
Slaven Falamić
Eligibility Criteria
Inclusion Criteria
- •Age ≥65 years
- •Living site of participant outside the city eg. rural site
- •Expected duration of warfarin therapy at least 6 months from the inclusion in the study and 3 months before
Exclusion Criteria
- •Hospitalization
- •Vegetarianism
- •Patients not able to provide an informed consent
- •The use of drug that has an X level of clinical significance of interaction with warfarin according to Lexicomp interact base
Outcomes
Primary Outcomes
Time in therapeutic range (TTR)
Time Frame: 6 months
Time in therapeutic range by Rosendaal method (percentage of time in therapeutic range)
Secondary Outcomes
- Adverse drug reactions(6 months)
- Adherence(6 months)
- International randomised ratio(6 months)
- Quality of life(6 months)
- Acceptance of pharmacist's intervention by the general practitioners(6 months)
- Time to adverse drug reaction(6 months)
- Dietary intake of vitamin K(6 months)
- Incidence and influence of clinically significant drug interactions(6 months)
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