Comparison of two drugs for quality of block in spinal anaesthesia
Completed
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2022/08/044717
- Lead Sponsor
- IVY hospital mohali
- Brief Summary
Comparison between dexmedetomidine and fentanyl, used as additive to 0.5% hyperbaric bupivacaine in spinal anaesthesia, for quality and duration of sensory-motor block and for duration of postoperative analgesia in patients undergoing total knee arthroplasty. Control group is the one in which normal saline is used as additive to 0.5% hyperbaric bupivacaine in spinal anaesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
ASA grade I and II posted for total knee arthroplasty under spinal anaesthesia.
Exclusion Criteria
- ASA grade III and IV with severe systemic illness 2.
- Pregnancy 3.
- Patient with history of heart conduction abnormalities 4.
- Patient on alpha blockers 5.
- Any known hypersensitivity to the study drugs 6.
- Any contraindications to SA such as local infection, coagulopathy.
- Patient with neurologic disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method duration and quality of sensory-motor block in spinal anaesthesia and duration of postoperative analgesia duration of motor anaesthesia (time taken to reach Bromage 0 from Bromage III after administration of subarachnoid block) and time of first rescue analgesia (the first time patient complains of pain at surgical site after administration of subarachnoid block)
- Secondary Outcome Measures
Name Time Method Effect on hemodynamics plus any intraoperative and/or postoperative complications
Trial Locations
- Locations (1)
IVY hospital, mohali
🇮🇳Rupnagar, PUNJAB, India
IVY hospital, mohali🇮🇳Rupnagar, PUNJAB, IndiaDr Shalini SPrincipal investigator7340941441dr.shalu83@gmail.com