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The threonine requirement in preterm neonates. De behoefte aan threonine in de voeding van de preterm geboren neonaat.

Recruiting
Conditions
neonates, preterms, LBWI, nutrition, amino acidsneonaten, prematuren, voeding, aminozuren
Registration Number
NL-OMON26530
Lead Sponsor
Erasmus MC Sophia BV
Brief Summary

ysine requirement of the enterally fed term neonate in the first month of life.<br> Huang L, Hogewind-Schoonenboom JE, de Groof F, Twisk JW, Voortman GJ, Dorst K, Schierbeek H, Boehm G, Huang Y, Chen C, van Goudoever JB Am J Clin Nutr. 2011 Dec;94(6):1496-503.

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
35
Inclusion Criteria

Preterm infants with a gestational age of 30-35 weeks, a postnatal age of 28 days and a birth weight of less than 2200 gram.

Exclusion Criteria

1. Congenital anomalies;

2. Sepsis;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The mean requirement of threonine in preterm neonates by breakpoint estimation. This will be determined by applying a two-phase linear regression crossover model.
Secondary Outcome Measures
NameTimeMethod
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