A Randomized Comparative Clinical Study To Evaluate The Efficacy Of Shunthiyadi kwatha and Pashanabhedadi kwatha In Mutrashmari WSR Urolithiasis
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
Urolithiasis is a pathological condition of the urinary system characterized by the formation of urinary calculi anywhere in the urinary tract, from the kidneys to the urinary bladder, posing a significant challenge to healthcare systems. Etiological factors include dietary habits, vitamin A deficiency, hot climate, low citrate levels, urinary stasis, kidney infections, prolonged immobilization, medullary sponge kidney, hyperparathyroidism, hyperoxaluria, cystinuria, and renal tubular acidosis.
Globally, the prevalence of urolithiasis is increasing due to changes in lifestyle, dietary patterns, climate, and comorbid conditions. Current management strategies include conservative treatments, lifestyle modifications, and surgical interventions, yet recurrence rates remain high, highlighting the need for alternative or adjunct therapies.
This study is designed to evaluate the efficacy of Shunthiyadi Kwatha compared to Pashanabhedadi Kwatha, aiming to expand treatment options and improve patient outcomes. The study is entitled:
"A Randomized Comparative Clinical Study to Evaluate the Efficacy of Shunthiyadi Kwatha and Pashanabhedadi Kwatha in Mutrashmari with Special Reference to Urolithiasis."
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients Of Either Sex Male Or Female.
- •Patients Of Age Group From 18 to 60 Years.
- •Patient having renal and ureteric stones with Size Upto Less Than Or Equal To 10mm Will Be Include In This Trial .
排除标准
- •1.Age Below 18 Years And More Than 60 Years.
- •2.Patient With Obstructive Uropathy.
- •3.Patient With Chronic Kidney Diseases, Nephrotic Syndrome.
- •4.Patient With Hydronephrosis .(Grade3 And Grade4) Grade 3 (Moderate)- Moderate Dilation Of The Renal Pelvis And Calyces.
- •Blunting Of Fornices And Flattening Of Papillae Mild Cortical Thinning May Be Seen.
- •Grade 4 (severe)- Gross Dilation Of The Renal Pelvis And Caleyes, Which Appear Ballooned .
- •Loss Of Border Between The Renal Pelvis And Calcyes.
- •Renal Atrophy Seen As Cortical Thinning 5.Patient With Evidence Of Malignancy.
- •6.Patient With Poorly Controlled Diabetes Mellitus (HBA1C More Than 8%).
- •7.Pregnant Or Lactating Women.
- •8.Symptomatic Patients With Clinical Evidence Of Heart Failure.
- •9.Patient With Urolithiasis (Mutrashmari) With Complication, Such As AcutE Renal Failure, Sepsis, Anuria, Urinary Tract Infection With Renal Obsturction 10.Urinary Stones Of More Than 10mm Size.
- •11.Uncontrolled Hypertension (Systolic Blood Pressure More Than 160mmHg Or Diastolic Blood Pressure More Than 100 mmHg).
- •12.Presence Of Any Other Serious Medical Condition That May Interfere With Study Participation.
研究者
DR KOMAL GUPTA
National Institute of Ayurveda, Deemed to be university, Jaipur