Heparin Solution and INTEM/HEPTEM Analysis

Completed

• Conditions: Brain Tumor; Spinal Stenosis; Cerebral Artery Anuerysm
• Interventions: Drug: Heparin

• Registration Number: NCT01522846
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

Heparinized solution has been used for maintenance of arterial catheter during perioperative period. Although the infused dose of heparin is very low, the investigators examine whether the heparin effect is remained or not in blood using rotational thromboelastometry (ROTEM) analysis.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2012-01-09
• Study First Submitted QC: 2012-01-27
• Study First Posted: 2012-02-01
• Primary Completion: 2013-01
• Study Completion: 2013-01
• Status Verified: 2013-08
• Last Update Submitted: 2013-08-28
• Last Update Posted: 2013-08-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Patients requiring continuous invasive arterial pressure monitoring during operation for anesthetic management.

Exclusion Criteria

• heparin hypersensitivity
• hematologic disease
• anticoagulant medication

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Heparin	Heparin	-

Primary Outcome Measures

Name	Time	Method
INTEM test	at 30 min before operation and 30 min after operation	INTEM is not an abbriviation. INTEM is one of the ROTEM test and it is an coagulation test name (such as prothrombin time test) using patient's whole blood. We put the blood sample of patinet into the machine, so the result comes out automatically. It will be checked twice at pre- and postopertive 30 minute and it'll be analyzed and compared.
HEPTEM test	at 30 min before operation and 30 min after operation	HEPTEM is not an abbriviation. HEPTEM is one of the ROTEM test and it is an coagulation test name (such as prothrombin time test) using patient's whole blood. We put the blood sample of patinet into the machine, so the result comes out automatically. It will be checked twice at pre- and postopertive 30 minute and it'll be analyzed and compared.

Secondary Outcome Measures

Name	Time	Method
Total infused units of heparin	periond from starting operation to finishing operation (espected average of 5 hours).

Trial Locations

Locations (1)

Seoul National University Bundang Hospital; 🇰🇷 Seonnam, Gyounggi, Korea, Republic of