Catheter-related Bloodstream Infections in Patients With Intestinal Failure Receiving Home Parenteral Support: Risks Related to a Catheter-salvage-strategy.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 715
- 试验地点
- 1
- 主要终点
- new catheter-related bloodstream infections
研究概览
简要总结
This is an observational study evaluating a catheter salvage strategy in relation to catheter-related bloodstream infections in patients with chronic intestinal failure dependent on home parenteral support. The study is confined to the period 2002 to 2016.
详细描述
In chronic intestinal failure patients receiving home parenteral support (HPS), catheter-related bloodstream infections (CRBSIs) frequently results in replacement of their tunneled central venous catheters (CVCs) which may lead to future loss of central venous access.
This observational study investigates the consequences of a catheter-salvage-strategy related to CRBSIs according to different causative microorganisms, and short- and long-term risk of recurrence of the CRBSI. The study is based on the Copenhagen Intestinal failure database, which is a web-based database with retrospective data collection performed by reviews of medical charts from all adult intestinal failure patients discharged with home parenteral support from the Department of Medical Gastroenterology, Rigshospitalet.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic intestinal failure dependent on home parenteral support and enrolled in the Copenhagen Intestinal failure database
排除标准
- •Never discharged on home parenteral support
结局指标
主要结局
new catheter-related bloodstream infections
时间窗: 2002 to 2016
The occurrence of catheter-related bloodstream infection after either catheter salvaged (retained central venous catheter) or replaced central venous catheter (new central venous catheter)
次要结局
- recurrent catheter-related bloodstream infections(2002 to 2016)
- relapse catheter-related bloodstream infection(2002 to 2016)
- primary salvage rate(2002 to 2016)
研究者
Palle Bekker Jeppesen
Professor, MD
Rigshospitalet, Denmark