Attentional interference by itch and pai
Completed
- Conditions
- aandoeningen die gepaard gaan met (chronische) jeuk en pijnItchpruritusPain
- Registration Number
- NL-OMON46015
- Lead Sponsor
- niversiteit Leiden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Healthy volunteer* 18-30 years old* fluent in Dutch language
Exclusion Criteria
Severe or long-term physical or psychiatric morbidity (e.g., multiple sclerosis, diabetes mellitus, heart or lung disease, rheumatoid arthritis, vasculitis, major depressive disorder, atopic dermatitis, migraine), use of pacemaker, chronic itch or pain complaints, current use of medication (e.g., antihistaminics, analgesics), pregnancy.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Behaviourally, attentional interference, reflected by reaction times and<br /><br>accuracy for visual targets during the SAT, will be compared between itch and<br /><br>pain stimulation and vibrotactile stimulation. Neurophysiologically,<br /><br>attentional interference, reflected by EEG alpha desynchronization, will be<br /><br>compared between itch and pain stimulation compared to vibrotactile<br /><br>stimulation.</p><br>
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link attentional interference to chronic pruritus and pain in NL-OMON46015?
How does attentional interference from itch and pain compare to other sensory disturbances in treatment adherence?
Which biomarkers predict attentional interference severity in chronic pruritus and pain patients in the Leiden University study?
What adverse events are associated with attentional interference in chronic itch and pain management, and how are they mitigated?
Are there pharmacological agents targeting central nervous system pathways to reduce attentional interference in pruritus and pain?