NCT02104934已完成不适用
A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Local Infiltration Analgesia for Postoperative Analgesia After Total Knee Arthroplasty
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Morphine consumption in the first 24 hours
研究概览
简要总结
Total knee arthroplasty or replacement (TKA), a commonly performed surgery for osteoarthritis of the knee, is a painful procedure and requires a multimodal analgesic approach. A method for analgesia is local infiltration analgesia (LIA), where a mixture of drugs is injected around the knee joint.
Adductor canal block (ACB) is an alternative regional anaesthesia technique which has been shown to result in minimal thigh weakness.
The investigators aim to study if the analgesia provided by ACB is superior to LIA while preserving quadriceps strength.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 45 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for primary TKA under single shot spinal anaesthesia, between ages 45-85 years old, American Society of Anesthesiologists (ASA) physical status 1 to 3 and BMI 18-35 kg/m2
排除标准
- •Patients unable to give consent, inability to communicate/ cooperate, patients with regular consumption of strong opioids (morphine, oxycodone) or steroids, allergy to local anaesthetics or any drugs included in the study, patients with lower limb surgery in the preceding year, patients with pre-existing neurological deficits and patients who have contraindications for spinal anaesthesia.
结局指标
主要结局
Morphine consumption in the first 24 hours
时间窗: 24 hours
morphine consumption in the first 24 hours (including morphine administered in recovery and via PCA).
次要结局
- Sedation Scores(Up to 48 hours)
- Quadriceps Strength(at 24 and 48 hours)
- Morphine Consumption(At 48 hours)
- Pain Scores(1, 6, 12, 24 hours; up to 48 hours postoperative)
- Postoperative Nausea and Vomiting(Up to 48 hours)
研究者
研究点 (1)
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