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Clinical Trials/NCT02104934
NCT02104934
Completed
N/A

A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Local Infiltration Analgesia for Postoperative Analgesia After Total Knee Arthroplasty

Changi General Hospital1 site in 1 country40 target enrollmentMarch 2014
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ConditionsAnalgesia in Total Knee Arthroplasty

Overview

Phase
N/A
Intervention
Not specified
Conditions
Analgesia in Total Knee Arthroplasty
Sponsor
Changi General Hospital
Enrollment
40
Locations
1
Primary Endpoint
Morphine consumption in the first 24 hours
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Total knee arthroplasty or replacement (TKA), a commonly performed surgery for osteoarthritis of the knee, is a painful procedure and requires a multimodal analgesic approach. A method for analgesia is local infiltration analgesia (LIA), where a mixture of drugs is injected around the knee joint.

Adductor canal block (ACB) is an alternative regional anaesthesia technique which has been shown to result in minimal thigh weakness.

The investigators aim to study if the analgesia provided by ACB is superior to LIA while preserving quadriceps strength.

Registry
clinicaltrials.gov
Start Date
March 2014
End Date
March 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Patients scheduled for primary TKA under single shot spinal anaesthesia, between ages 45-85 years old, American Society of Anesthesiologists (ASA) physical status 1 to 3 and BMI 18-35 kg/m2

Exclusion Criteria

  • •Patients unable to give consent, inability to communicate/ cooperate, patients with regular consumption of strong opioids (morphine, oxycodone) or steroids, allergy to local anaesthetics or any drugs included in the study, patients with lower limb surgery in the preceding year, patients with pre-existing neurological deficits and patients who have contraindications for spinal anaesthesia.

Outcomes

Primary Outcomes

Morphine consumption in the first 24 hours

Time Frame: 24 hours

morphine consumption in the first 24 hours (including morphine administered in recovery and via PCA).

Secondary Outcomes

  • Sedation Scores(Up to 48 hours)
  • Quadriceps Strength(at 24 and 48 hours)
  • Morphine Consumption(At 48 hours)
  • Pain Scores(1, 6, 12, 24 hours; up to 48 hours postoperative)
  • Postoperative Nausea and Vomiting(Up to 48 hours)

Study Sites (1)

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