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Clinical Trials/NCT02033603
NCT02033603
Unknown
Not Applicable

A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Femoral Nerve Block for Analgesia Post Total Knee Arthroplasty

Changi General Hospital1 site in 1 country30 target enrollmentJanuary 2014
InterventionsRopivacaine

Overview

Phase
Not Applicable
Intervention
Ropivacaine
Conditions
Knee Osteoarthritis
Sponsor
Changi General Hospital
Enrollment
30
Locations
1
Primary Endpoint
Morphine consumption
Last Updated
11 years ago

Overview

Brief Summary

Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages. It is a painful surgery and one of the methods to reduce post-operative pain is performing a regional anaesthesia technique. The current practice is to perform a femoral nerve block (FNB) which blocks the nerves supplying the knee joint and the thigh muscles (quadriceps). This provides effective analgesia. However, it also results in weakness of the quadriceps and may result in falls post-operatively.

Adductor canal block (ACB) is a new, alternative regional anaesthesia technique which is hypothesised to provide as effective analgesia, with less quadriceps weakness compared to FNB, hence potentially reducing the risk of falls post-operatively.

Investigators aim to study if the analgesia provided by ACB is as good as FNB while preserving quadriceps strength.

Registry
clinicaltrials.gov
Start Date
January 2014
End Date
December 2014
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • ages 45-85
  • American Society of Anaesthesiologists physical status 1-3
  • BMI 18-35 kg/m2

Exclusion Criteria

  • inability to give consent, communicate, cooperate
  • Patients with regular consumption of strong opioids (morphine, oxycodone) or steroids
  • Patients with allergy to local anaesthetics or any drugs included in the study
  • Patients with lower limb surgery in the preceding year
  • Patients with pre-existing neurological deficits
  • Patients who are unsuitable for general anaesthetics (eg difficult airway)

Arms & Interventions

Femoral Nerve Block

Femoral Nerve block performed with 0.5% Ropivacaine 30mls (150mg)

Intervention: Ropivacaine

Adductor Canal block

Adductor Canal block performed with 0.5% Ropivacaine 30mls (150mg)

Intervention: Ropivacaine

Outcomes

Primary Outcomes

Morphine consumption

Time Frame: first 24 hours

Secondary Outcomes

  • Quadriceps strength, ability to mobilise(24, 48 hours)
  • Side effects of opioids- sedation, nausea and vomiting(48 hours)
  • Morphine consumption(48 hours)
  • Pain scores(1, 6, 12, 24, 48)

Study Sites (1)

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