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Biomagnetic Signals of Intestinal Ischemia II

Completed
Conditions
Ischemia
Registration Number
NCT00179036
Lead Sponsor
Vanderbilt University Medical Center
Brief Summary

The lack of blood flow to the small intestine causes mesenteric ischemia. Using a Superconducting QUantum Interference Device (SQUID) which measures the magnetic field of the small intestine, we are hoping to identify abnormalities without surgical intervention.

Detailed Description

The electrical activity of the small intestine may contain important information that will help us diagnose gastrointestinal diseases. The major impediment to reducing mortality of mesenteric ischemia is the lack of a noninvasive diagnostic test that identifies the syndrome before extensive necrosis occurs. Mesenteric ischemia is caused by the lack of blood flow to the intestine. The Superconducting QUantum Interference Device (SQUID) measures the magnetic field of the intestinal smooth muscle. By comparing normal smooth muscle and that of patients with mesenteric ischemia, the investigators hope to identify abnormal disease states without surgery.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
17
Inclusion Criteria
  • Normal subjects and those with diagnosed mesenteric ischemia
Exclusion Criteria
  • Subjects who report a tendency toward claustrophobia

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To observe a difference in the magnetic activity between the normal and diseased smooth muscle of the small intestine2010
Secondary Outcome Measures
NameTimeMethod
Create mathematical and computer models of electrical activity of smooth muscle2010

Trial Locations

Locations (1)

Vanderbilt University Medical Center

🇺🇸

Nashville, Tennessee, United States

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