Consequences of a Brain Lesion or of Migraine on Auditory Processing: Attention, Memory and Emotion

Hospices Civils de Lyon2 sites in 1 country262 target enrollmentFebruary 6, 2015

ConditionsMigraine Disorders, Brain

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Migraine Disorders, Brain
Sponsor: Hospices Civils de Lyon
Enrollment: 262
Locations: 2
Primary Endpoint: Percentages of correct responses in Neuropsychological tests
Status: Completed
Last Updated: 8 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The project studies auditory processing after brain damage (in temporal and/or frontal areas) and in migraine. The auditory processes investigated are attention, short-term memory, sound-induced emotions. To characterize auditory deficits after brain damage or in migraine, neuropsychological assessments are combined with neurophysiological markers (Electro-encephalography: EEG, Magneto-encephalography: MEG, Magnetic Resonance Imaging: MRI).

Registry

clinicaltrials.gov

Start Date

February 6, 2015

End Date

September 9, 2020

Last Updated

8 months ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Hospices Civils de Lyon

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age from 18 to 80
•MEG/MRI compatibility
•Motivation to participate efficiently in the study
•No severe hearing loss
•Informed consent to participate in the study
•Affiliation to social security
•For brain-damaged patients : no need for medical assistance; focal temporal and/or frontal lesion; no major cognitive impairment; ability to understand and apply the instructions for neuropsychological testing; testing at least one-month after the event resulting in brain damage; absence of neurological and psychiatric disorders besides the lesion
•For migraine patients: no need for medical assistance; migraine diagnosis; no major cognitive impairment; ability to understand and apply the instructions for neuropsychological testing; absence of neurological and psychiatric disorders besides the migraine
•Healthy participants: absence of neurological and psychiatric disorders

Exclusion Criteria

•Age below 18 or above 80
•MRI scanning not possible: artificial cardiac pacemaker, insulin pump, metallic prosthesis, intra-cerebral clip, claustrophobia
•MEG acquisition not possible: large heads, neurostimulator, metal in the head or the body.
•Pregnant or breast-feeding women