Brain Function and Perfusion in Patients With Heart Failure

University Medical Center Groningen1 site in 1 country45 target enrollmentJanuary 2012

ConditionsHeart Failure Dilated Cardiomyopathy Perfusion Cognitive Impairment Cerebral Hypoperfusion

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Heart Failure
Sponsor: University Medical Center Groningen
Enrollment: 45
Locations: 1
Primary Endpoint: Determinants of cerebral impairment
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The investigators will evaluate the determinants of cerebral impairment in patients with non-ischemic heart failure compared to controls, and its relation to cognitive function. They hypothesize that patients with heart failure have impaired brain perfusion and hemodynamic factors are associated with cognitive dysfunction.

Registry

clinicaltrials.gov

Start Date

January 2012

End Date

December 2012

Last Updated

13 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University Medical Center Groningen

Responsible Party

Principal Investigator

A.A.Voors

Prof. dr.

University Medical Center Groningen

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

Determinants of cerebral impairment

Time Frame: Baseline

Determinants of cerebral impairment in patients with heart failure compared to controls, where cerebral impairment is defined as decreased cognitive function and cerebral hypoperfusion

Secondary Outcomes

Prevalence of cognitive impairment(Baseline)
Relation of cognitive impairment with local perfusion(Baseline)
Relation of cognitive impairment with the severity of heart failure(Baseline)
Relation of cognitive impairment with cardiac output(Baseline)
Relation of cognitive impairment with the severity of congestion(Baseline)
Relation of cognitive impairment with the decrease in cerebral perfusion(Baseline)
The difference of cognitive domains in above relations(Baseline)