Role of Vonaprazan in H.Pylori eradicatio

Phase 3

Recruiting

• Conditions: Helicobacter pylori infection is a condition in which gram -ve bacteria called H- pylori reside in mucus lining of stomach lead to gastritis, ulcer manifest in the form of dyspepsia.; Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere; B96.81

• Registration Number: IRCT20221207056738N1
• Lead Sponsor: ational university of Medical Sciences Rawalpindi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

Positive stool antigen test for h-pylori,endoscopic histopathological evidence of h-pylori.
Age 18 years and above
Both male and female patients presented with symptoms of dyspeps

Exclusion Criteria

Patient with history of drug allergy to either Pantoprazole, Vonoprazan
Vonoprazan, penicillin’s or clarithromycin ,
Previous h-pylori eradication therapy,
Pregnant and breast-feeding mothers,
Patient with serious CVS, liver, renal, pulmonary disorders or acute malignancy,
,History of gastric malignancy or surgery,
History of drug abuse.
History of using anti-biotics that affect h-pylori with in 4 weeks

Study & Design

• Study Type: interventional
• Study Design: Not specified