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A clinical trial to study the effects of two radiotherapy schedules, conventional and hypofractionated, following mastectomy operation in female breast cancer patients with locally advanced disease

Phase 2
Completed
Conditions
Health Condition 1: null- Adjuvant Radiotherapy in Female Breast Cancer Patients
Registration Number
CTRI/2018/04/013174
Lead Sponsor
Dr Partha Pratim Medhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
50
Inclusion Criteria

Female patients with histologically confirmed invasive breast cancer, who underwent modified radical mastectomy and planned for adjuvant radiotherapy as per Institutional Tumour Board decision

Patients tumours with pathological stage IIA-IIIC

Any patient who had received neoadjuvant chemotherapy

Patients with normal haematological, cardiac and pulmonary functions prior to radiotherapy

Patients must provide study specific informed consent prior to study entry.

Exclusion Criteria

Patients with clinical N3 disease with metastatic supraclavicuar lymphadenopathy

Patients with Stage IV metastatic disease

Patients with tangential beam margins separation more than 22 cm

Patients with non-epithelial malignancies

Patients with co-existent or previous history of other malignancy

Patients who received prior radiotherapy to chest wall region

Patients with severe physical or mental co-morbidities

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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