The Effect of Salmetrol, Tiotropium, and their Combination in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)
Phase 2
Recruiting
- Conditions
- Chronic obstructive pulmonary disease.Other chronic obstructive pulmonary disease
- Registration Number
- IRCT20190123042466N1
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 108
Inclusion Criteria
Patients with acute exacerbation of COPD
Age over 35 years
Spirometry or previous histories consistent with chronic obstructive pulmonary disease
Patients reporting at least 10 packets of cigarette smoking
Exclusion Criteria
Acute coronary syndrome
Severe associated comorbidities (cardiac and renal)
Patients with a recent history of myocardial infarction
Patients with prostate hypertrophy and closed glaucoma
Patients with allergic rhinitis or atopy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dyspnea in daily living. Timepoint: At the beginning of the study and 15 days after the start of treatment. Method of measurement: The modified Medical Research Council scale.;Severity of chronic obstructive pulmonary disease. Timepoint: At the beginning of the study and 15 days after the start of treatment. Method of measurement: Chronic obstructive pulmonary disease assessment Test.
- Secondary Outcome Measures
Name Time Method Arterial blood gas parameters. Timepoint: At the beginning of the study and 15 days after the start of treatment. Method of measurement: Arterial blood gases.