JPRN-UMIN000027045
Completed
未知
Diagnosis and elucidation of small-fiber dysfunction using electrophysiological technique - Diagnosis and elucidation of small-fiber dysfunction using electrophysiological technique
Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine0 sites40 target enrollmentApril 18, 2017
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Pain detection threshold using intraepidermal electrical stimulation (IES) and cooling detection threshold using quantitative sensory testing (QST) were positively correlated. Amplitude of evoked potentials (EPs) following electrical stimulation using IES was negatively correlated with pain and cooling detection thresholds. Sensory thresholds and amplitude of EPs were deteriorated with length-dependent pattern in patients with familial amyloid polyneuropathy. These results support a notion that IES is a useful clinical tool for evaluating small-fiber dysfunction.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Patients or healthy subjects with other neuropathy
Outcomes
Primary Outcomes
Not specified
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