Effect of Allopurinol on Chronic Kidney Disease Progression.
Not Applicable
- Conditions
- Chronic renal failure.Chronic renal failure
- Registration Number
- IRCT2015101714333N43
- Lead Sponsor
- Vice chancellor for research, Kermanshah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
informed consent of the patient;the diagnosis of renal glomerular filtration ;(GFR) of less than 60 and over 15; uric acid greater than 6 mg per dL; age over 18 years; no history of hospitalization during the past three months due to renal disease and no increase in creatinine number greater than 50% compared to the 3months ago.
Exclusion criteria: allopurinol intolerance;allergy; the possibility of pregnancy; liver disease history of gout
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method GFR level. Timepoint: At beginning of the study, and at 3,6 and 12 months after study. Method of measurement: Using the formula Modification of Diet in Renal Disease(MDRD).;Using the formula creatinine. Timepoint: At beginning of the study, and at 3,6 and 12 months after study. Method of measurement: Based on blood tests.;Uric acid. Timepoint: At beginning of the study, and at 3,6 and 12 months after study. Method of measurement: Based on blood tests.
- Secondary Outcome Measures
Name Time Method