ACTRN12612000778886尚未招募未知
ebulised frusemide to improve the sensation and unpleasant feeling of dyspnoea in patients with advanced diseases and breathlessness refractory to optimal standard management
Dr Maria Cristina Cigolini0 个研究点目标入组 45 人开始时间: 2012年7月23日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Primary diagnosis of any irreversible disease. Prognosis of the disease needs to be less than 12 months.
- •-Refractory dyspnoea that is not reponsive to more establisehd therapies.
- •-Any concomitant disease but not rapidly deteriorating
- •-Willingness to give informed consent documented by the treating team and willingness to participate and comply with the study
排除标准
- •-Unwilling/unable to give informed consent
- •-Unable to tolerate frusemide
- •-Rapid deterioration
- •-Hepatic encephalopathy
- •-Anuric renal failure
- •-Mental or cognitive disorder, unable to reliably self-report or consent
- •-Significant hypotension with the risk of further pronounced drop in blood pressure
- •-Currently receiving risperidone
- •-Significant history of gout
- •-Significant change in medication that may affect dyspnoea within the last 24 hours
- •-Hypersensitivity to frusemide or any inactive ingredient
- •-Actively receiving treatment for dyspnoea, for example pleural effusion drainage or blood transfusion
- •-Electrolyte disturbance
- •-Aversion/inability to fit mask
研究者
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