Evaluation of effect of furosemide add on to hypertonic slain on neurohormonal factors in Traumatic brain injury

Not Applicable

• Conditions: brain injury.; Concussion,Traumatic cerebral oedema, Diffuse brain injury, Focal brain injury, Epidural haemorrhage,Traumatic subdural haemorrhage,Traumatic subarachnoid haemorrhage, Intracranial injury with prolonged coma, Other intracranial injuries, Intracranial inju; S06.0-S06-

• Registration Number: IRCT201509283014N10
• Lead Sponsor: Mazandaran University of Medical Sciences, Vice chancellor for research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

All of patients with 18-90 years old with closed head trauma ; associated with brain edema confirmed with CT scan
; Hemodynamically stable before management; GCS<14; Patients with CV line
; admission with in 24 hours of initial insult

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bloood Na. Timepoint: 1,2.3.4 days. Method of measurement: Serum concentraion.;Blood osmolality. Timepoint: 1,2,3,4 days. Method of measurement: With calculation of ions affect the osmolarity.

Secondary Outcome Measures

Name	Time	Method
??S100B. Timepoint: 1,2,3,4 days. Method of measurement: Kit (spectrophotometery).;NSE. Timepoint: 1,3,5. Method of measurement: Kit (spectrophotometery).