NCT00960232已完成3 期
Vitamin D, Blood Pressure, Lipids, Infection and Depression
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Depression score
研究概览
简要总结
There are numerous indications for a relation between low serum levels of 25(OH)D and blood pressure, lipid levels, frequency of infections and tendency towards depression. Whether it is a causal relationship it is not known, and can best be studied with a vitamin D intervention. The investigators hypothesis is that supplementation with a high dose vitamin D (40.000 IU per week) will have a beneficial effect on these parameters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •men and women 30 - 75 years of age
- •low serum 25(OH)D levels
排除标准
- •other serious diseases
- •hypercalcemia
研究组 & 干预措施
Placebo
Placebo Comparator
Placebo
干预措施: placebo (Drug)
Vitamin D
Experimental
vitamin D 40.000 IU per weel
干预措施: Cholecalciferol (Drug)
结局指标
主要结局
Depression score
时间窗: 6 months
Blood pressure
时间窗: 6 months
Lipid profile
时间窗: 6 months
Frequency of infections
时间窗: 6 months
次要结局
未报告次要终点
研究者
研究点 (1)
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