Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

Not Applicable

Completed

• Conditions: Total Knee Arthroplasty
• Interventions: Procedure: Running Subcuticular Closure; Procedure: Vertical Mattress Closure; Procedure: Staple Closure

• Registration Number: NCT01924403
• Lead Sponsor: Mayo Clinic

Brief Summary

This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion. This can be achieve by using SPY intra-operative vascular angiography, which is commonly used in clinical practice to assess perfusion of wound closure at the clinic. By understanding the differences in perfusion afforded by different closure techniques, surgeons will then be able to select the technique that optimizes this parameter so as to avoid complications such as tissue necrosis, wound dehiscence, or infection.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-08
• Study First Submitted: 2013-08-14
• Study First Submitted QC: 2013-08-14
• Study First Posted: 2013-08-16
• Primary Completion: 2014-07
• Study Completion: 2014-07
• Status Verified: 2015-02
• Last Update Submitted: 2015-02-13
• Last Update Posted: 2015-02-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• ≥ 18 years old
• Primary diagnosis of osteoarthritis
• Surgical indication for index total knee arthroplasty

Exclusion Criteria

• Previous surgery about the knee
• Systemic corticosteroid use
• Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Running Subcuticular Closure	Running Subcuticular Closure	Running subcuticular closure will be one technique employed to close the wound in primary total knee arthroplasty.
Vertical Mattress Closure	Vertical Mattress Closure	Vertical mattress closure will be one technique employed to close the wound in primary total knee arthroplasty.
Staple Closure	Staple Closure	Staple closure will be one technique employed to close the wound in primary total knee arthroplasty.

Primary Outcome Measures

Name	Time	Method
Perfusion of Wound Closure	Surgical Point of Care

Trial Locations

Locations (1)

Mayo Clinic in Rochester; 🇺🇸 Rochester, Minnesota, United States