Evaluation of Wound Dressings in the Reduction of Shear- Force

Completed

• Conditions: Pressure Ulcer

• Registration Number: NCT02348671
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

The purpose of this study is to investigate if wound dressings are capable in reducing the effects of shear- force at the skin. With our own shear- force model we are able to apply 19 Newton shear- force combined with 9 newton pressure at the skin of the non- dominant forearm. After half an hour we measure IL-1alpha/ total protein- ratio, cutaneous blood flow (Laser doppler, Moor LDI) and the erythema index (DSMIIColormeter) which occurs as an effect of shear- force application at the skin.

Then, we apply 19 Newton shear- force combined with 9 Newton pressure at the dominant fore-arm but this time we put a wound dressing between the skin and shear- force model. After half an hour we measure the IL-1alpha/total protein-ratio, cutaneous blood flow and the erythema index.

This research consists of three research day, each day we are going to investigate a different wound dressing

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-12-01
• Status Verified: 2015-01
• Study First Submitted QC: 2015-01-22
• Study First Posted: 2015-01-28
• Study Start: 2015-03
• Primary Completion: 2015-06
• Study Completion: 2015-07
• Last Update Submitted: 2015-09-22
• Last Update Posted: 2015-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

• healhty volunteer
• age 18- 30
• BMI 20- 30

Exclusion Criteria

• Trauma fore-arms
• Diabetes mellitus type I or type II
• The use of NSAID's in the last 7 days
• Vascular diseases
• Muscular dystrophy
• Malignancy
• Participant is unable to give informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cutaneous blood flow, erythema index, IL-1alpha/Total protein ratio	Directly after intevention