Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.

Phase 2

Completed

• Conditions: Wound Surgical; Wound Infection; Wound Bleeding; Wound Dehiscence
• Interventions: Drug: Iodine Dressing; Biological: Honey Dressing

• Registration Number: NCT06220344
• Lead Sponsor: HITEC-Institute of Medical Sciences

Brief Summary

The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other co-morbidities like Diabetes, Anemia, etc. which can make the results biased. The main questions it aims to answer are:

* Do the iodine solutions are enough to counter the infections caused by resistant strains of bacteria?

* What is the efficacy and efficiency of honey dressing in wound care?

Participants will be tasked to

* Ensure strict follow-up in the hospital dressing room

* Half of the participants will apply common iodine solution dressing and the other half will be applied honey dressing.

Researchers will compare Iodine dressing (Control group) with Honey dressing (Experimental group) to see if Honey dressing is better in the prevention of post-surgery wound infection and if it is cost-efficient and its efficacy.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-02
• Primary Completion: 2023-03-03
• Study Completion: 2023-03-03
• Status Verified: 2024-01
• Study First Submitted: 2024-01-14
• Study First Submitted QC: 2024-01-14
• Study First Posted: 2024-01-23
• Last Update Submitted: 2024-01-23
• Last Update Posted: 2024-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients with sterile/clean post-surgical wounds are admitted in general surgery, neurosurgery, orthopedic, and gynecology wards and require follow-up dressings.

Exclusion Criteria

1. Patients with:

   • Anemia
   • BMI>30
   • Local Infection in wound area.
   • Venous leg ulcers
   • Diabetes
   • Immunocompromised (Oncological patients)

2. Patient under negative pressure therapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aseptic Iodine	Iodine Dressing	Participants will get iodine solution dressings in their follow-up visits to the dressing room.
Honey	Honey Dressing	Participants will get honey dressings in their follow-up visits to the dressing room.

Primary Outcome Measures

Name	Time	Method
Signs of Wound Infection	3rd day, 7th day, 15th day.	Presence of exudate, warmth, pus, erythema, dehiscence, contact bleeding, and any systemic sign like fever, rash, and myalgia.

Trial Locations

Locations (1)

Heavy Industry Taxila Hospital; 🇵🇰 Rawalpindi, Punjab, Pakistan