A clinical trial to compare the effects of two drugs, dexmedetomidine , a drug used in treatment of raised blood pressure and paracetamol , a drug used for pain relief in patients undergoing laparoscopic cholecystectomy.
Phase 4
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/10/046735
- Lead Sponsor
- DrGadde Venkata Harshitha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Consent to participate in the study
2.Patients scheduled for laparoscopic cholecystectomy
3.American society of anaesthesiology grade 1 and 2
Exclusion Criteria
1.Uncooperative patient/ not able to understand pain assessment test
2.Pregnant and lactating women
3.History of any significant pulmonary, cardiovascular, neurological, hepatorenal, pshyciatric or metabolic disease.
4.Bleeding diathesis.
5.History of previous allergy to paracetamol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dexmedetomidine and Paracetamol combination is more effective in maintaining the hemodynamic responses and intraoperative hemodynamic variables in laparoscopic cholecystectomy surgery than individual drugs.Timepoint: baseline, 24hours
- Secondary Outcome Measures
Name Time Method Postoperative pain is minimal with combination groupTimepoint: 24hours