The Effect of Pretreatment Submucosal Tramadol and Dexamethasone Injection on Postendodontic Pain in Mandibular Molar Teeth with Symptomatic Irreversible Pulpitis: A Randomized Controlled Clinical Trial

Not Applicable

Completed

• Conditions: postendodontic treatment pain in patients with symptomatic irreversible pulpitis; Dexamethasone, tramadol, postendodontic pain, symptomatic irreversible pulpitis

• Registration Number: TCTR20190529001
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-03-20
• Study Start: 2019-05-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

The inclusion criteria included systemically healthy patients, aged between 18 and 65 years, having mandibular molars with symptomatic irreversible pulpitis, preoperative pain score ranging from moderate to severe (55â€170 mm) on a Heft-Parker visual analog scale (HP-VAS, 0â€170 mm), radiographically normal periapical area and no pain on percussion.

Exclusion Criteria

The exclusion criteria comprised: pregnant or breastfeeding women, patients with allergy, sensitivity or adverse reactions to the medications administered in this study, those who had taken an analgesic or anti-inflammatory drug within last 12 hours before the treatment, those with unrestorable teeth, teeth with periodontal disease, root resorption, open apex, calcified root canals and pulpal necrosis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
controlling of postendodontic pain 6., 12.,24.,48. and 72 hours HP VAS Scale

Secondary Outcome Measures

Name	Time	Method
preparation pain 15 minutes HP VAS Scale