Fetal Doppler and Uterine Artery Blood Volume Correlation.

Completed

• Conditions: Fetal Doppler; Uterine Blood Flow
• Interventions: Other: Ultrasound exam

• Registration Number: NCT05389553
• Lead Sponsor: University of Campania "Luigi Vanvitelli"

Brief Summary

To investigate the relationship between uterine artery blood volume and fetal doppler indices at the delivery.

Detailed Description

Introduction: To investigate the relationship between uterine artery blood volume and fetal doppler indices at the delivery.

Materials and Methods: This was a prospective cohort study of 50 nulliparous women booking antenatal care at the University of Campania "Luigi Vanvitelli" between May 2022 and September 2022. All full-term pregnancies accepted for delivery will include. Pregnant women with antepartum haemorrhage, stillbirths, multiple gestations, or congenital abnormalities were excluded. Women underwent a transabdominal ultrasound examination of uterine arteries for measurement of Uterine artery blood volume. Pregnancy outcomes were recorded, and linear regression was used to study the relationship between uterine artery blood volume and fetal Doppler indices. SPSS version 25 (Chicago, IL, USA) was used to code, tabulate, and analyze the data. Quantitative data were analyzed using the student's t-test. Qualitative data were analyzed using the Mann-Whitney test. A statistically significant difference was defined as a p-value of 0.05.

Study Timeline

• Study First Submitted: 2022-05-20
• Study First Submitted QC: 2022-05-24
• Study First Posted: 2022-05-25
• Study Start: 2022-05-30
• Primary Completion: 2022-06-30
• Study Completion: 2023-10-31
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-23
• Last Update Posted: 2023-11-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 49

Inclusion Criteria

• full-term pregnancies (37-42 weeks)

Exclusion Criteria

• antepartum hemorrhage, fetal growth restriction, stillbirths, multiple gestations, or congenital abnormalities

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients at term of pregnancy	Ultrasound exam	We included all full-term pregnancies accepted for delivery that received an accurate ultrasound scan before the birth. Pregnant women with antepartum hemorrhage, fetal growth restriction, stillbirths, multiple gestations, or congenital abnormalities were excluded.

Primary Outcome Measures

Name	Time	Method
We estimate the uterine volume and its correlation with the fetal doppler indices	1 day	The volume of the uterine arteries will be measured using a doppler ultrasound. We shall also estimate the fetal doppler indices.; Linear regression will be used to test for a possible relationship between uterus volume blood flow and fetal doppler parameters. Before the delivery, all of these variables will be estimated using an ultrasound exam.

Trial Locations

Locations (1)

Università degli studi della Campania "Luigi Vanvitelli"- OB & Gyn -; 🇮🇹 Napoli, Italia, Italy