IRCT201611033664N18已完成2 期
The effect of genistein supplementation on metabolic parameters and oxidative stress in postmenopausal women with type 2 diabetes.
Vice-chancellor for research, Tabriz Nutrition Research Center, Tabriz University of Medical Science0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 45 years 至 64 years（—）
- 性别
- Female
入选标准
- •Willingness to participate in the study; Postmenopausal women with history of at least one year menopause ; menopause must not be a complication of surgery; Type-2 diabetes for at least 6 months; using blood glucose lowering drugs (metformin) .
- •Exclusion criteria: Unwillingness to participate in the study; Surgery leads to menopause; Early menopause (before 40 years); Use of androgen and estrogen and other steroids can affect the estrogen receptor; Insulin injections; Use of any nutritional supplements (omega-3) or anti-inflammatory and antioxidant supplements in the last 3 months or during the study; Liver and kidney failure, cardiovascular disease, breast cancer and thyroid disease; Smoking and alcohol; Patients taking NSAID, corticosteroids (prednisone, methylprednisolone, and hydrocortisone), antidiuretic thiazide (furosemide and hydrochlorothiazide) and anti psychotics second generation (olanzapine, clozapine and).
- •(All participants in the study shouldn't take these drugs at least three months before the study)
排除标准
- 未提供
研究者
相似试验
已完成
2 期
Effect of genistein supplementation on serum level of homocystein and PAI-1 (Plasminogen Activator Inhibitor-1) in postmenopausal women with type-2 diabetes mellitus.Type 2 diabetes mellitus.Type 2 diabetes mellitusIRCT20100408003664N23utritional Reseach Center of Tabriz University of Medical Sciences60
已完成
3 期
Treatment of non-alcoholic fatty liver diseasenon alcoholic fatty liver.Fatty (change of) liver, not elsewhere classifiedIRCT201506222480N6Shiraz University of Medical Sciences100
已完成
3 期
Treatment of non-alcoholic fatty liver diseaseon alcoholic fatty liver.Fatty (change of) liver, not elsewhere classifiedIRCT201312132480N5Shiraz University Of Medical Sciences100
尚未招募
不适用
Effect of dietary suppletion with genestein in patients with the MPS IIIMPS IIISanfilippo10021605NL-OMON32555Academisch Medisch Centrum30
已完成
不适用
Effect of Genestein as food supplement in patients with Sanfilippo syndrome.Sanfilippo syndrome (MPS III) comprises 4 closely related inborn errors of lysosomal degradation of the glycosaminoglycan heparan sulphate (GAGs). Accumulation of heparan sulfate, results in progressive and severe mental deterioration, which is the clinical hallmark of MPS III. Patients with MPS III usually die before the 3th decade. At present there is no causal therapy for patients with MPS III and treatment is symptomatic.NL-OMON21882AMC Amsterdam30