Study on innate immune Warburg response of Yupingfeng powder granules in repeated transplantation failure patients

Phase 1

Recruiting

• Conditions: repeated transplantation failure

• Registration Number: ITMCTR2100004304
• Lead Sponsor: Shanxi Maternal and Child Health Care Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

1. Those who meet the diagnostic criteria of traditional Chinese and Western medicine;
2. Signed informed consent;
3. Routine semen of the man showed no abnormality.
4. Aged 25~35 years;
5. No history of drug allergy or immunomodulatory drugs;
6. Adhere to oral Chinese medicine treatment.

Exclusion Criteria

1. Congenital malformed reproductive organs, endometrial polyps surgery, hydrosalpinx, etc.
2. Had endometriosis polycystic ovary syndrome such as endocrine system disease, endocrine related diseases such as diabetes and thyroid disease;
3. Patients with reproductive system infectious disease or in the acute phase of sexually transmitted diseases;
4. Cause infertility for chromosome abnormal or familial heredity disease;
5. Anticardiolipin antibodies, anti beta 2 glycoprotein antibody, antinuclear antibodies, antisperm antibody and anti endometrial antibody examination were positive;
6. Patients with cardiovascular disease and family history of infectious diseases such as tuberculosis;
7. Incorrect judgment of curative effect because of incomplete information or failure to take medicine as required;
8. Patients with no history of long-term use of drugs, no radioactive radiation, there is no history of trauma or drug allergy;
9. The male reproductive system and semen function are normal, and there is no maternal and child blood group mismatch
10. The patient had no bad habits such as smoking, taking drugs or drinking alcohol.
11. Suffer from mental illness or severe cardiovascular and cerebrovascular diseases.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The rate of pregnancy, the rate of abortion, the rate of carrying babies;