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2000 HIV Human Functional Genomics Partnership Program

Completed
Conditions
AIDS
HIV
10027665
10002252
10003216
Registration Number
NL-OMON52894
Lead Sponsor
Radboud Universitair Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
1910
Inclusion Criteria

- HIV1 infection
- Age >/= 18
- cART >=6 months with an HIV-RNA load <200 copies/mL
- Elite controllers will be included as well:
Viremic elite controllers:
- HIV-positive >5 year without cART AND
- with always HIV-RNA >50-10.000 copies/ml AND
- always CD4> 500 cells/uL, OR
- on cART, but before start cART >5 year without cART AND
- with always HIV-RNA >50-10.000 copies/ml AND
- always CD4> 500 cells/uL

Non-viremic elite controllers:
- HIV-positive > 1 year without cART AND
- with >3 consecutive HIV-RNA < 75 copies/ml spanning >12 months
AND
- stable CD4> 350 cells/uL, OR
- on cART, but before start cART > 1 year without cART AND
- with >3 consecutive HIV-RNA < 75 copies/ml spanning >12 months
AND
- stable CD4> 350 cells/uL

- No active hepatitis B/C or signs of acute infections

Exclusion Criteria

- Active hepatitic B/C or signs of acute infection
- Known malignancy
- Language barrier that limits effective communication
- Pregnancy

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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