Substance-focused SBI as a Complement to Internet-based Psychiatric Treatment: RCT

Not Applicable

Completed

• Conditions: Substance Use Disorders (SUD)

• Registration Number: NCT01885026
• Lead Sponsor: Karolinska Institutet

Brief Summary

Objectives: This study evaluates the efficacy of eScreen for internet psychiatry patients treated for major depressive disorder, panic anxiety and social phobia. The eScreen brief Internet intervention for problematic alcohol and drug use offers self-screening, in-depth self-reporting, personalized feedback and treatment recommendations as well as an electronic diary. Progress over time is shown in diagrams detailing consumption levels.

Method: This is a two-armed randomized controlled design, measuring outcomes in terms of changes in problematic alcohol use up to one year after study recruitment. Participants with problematic alcohol use (AUDIT \>7 for men and \>5 for women) and/or problematic drug use (DUDIT \> 1 for both men and women) are randomized into one of two groups: T1, eScreen referral or Control group. Outcomes on alcohol and drug use as well as health-related symptoms are assessed after 3, 6 and 12 months.

The hypothesis is that the group receiving the eScreen intervention will reduce their alcohol/drug use to a larger extent than the control group at follow-up compared to the baseline level.

Detailed Description

This study evaluated the efficacy of eScreen for internet psychiatry patients treated for major depressive disorder, panic anxiety and social phobia. The eScreen brief Internet intervention for problematic alcohol and drug use offers self-screening, in-depth self-reporting, personalized feedback and treatment recommendations as well as an electronic diary. Progress over time is shown in diagrams detailing consumption levels. The design was a two-armed randomized controlled design, measuring outcomes in terms of changes in problematic alcohol use up to one year after study recruitment. Participants with problematic alcohol use (AUDIT \>7 for men and \>5 for women) and/or problematic drug use (DUDIT \> 1 for both men and women) were randomized into one of two groups: T1, eScreen referral or Control group. Outcomes on alcohol and drug use as well as health-related symptoms are assessed after 3, 6 and 12 months.

The hypothesis was that the group receiving the eScreen intervention would reduce their alcohol/drug use to a larger extent than the control group at follow-up compared to the baseline level. The results have not yet been analyzed due to technical issues. However, qualitative interviews have been conducted with participants and our intention is to publish the qualitative results in tandem with the quantitative results available.

Study Timeline

• Study First Submitted: 2013-06-20
• Study First Submitted QC: 2013-06-20
• Study First Posted: 2013-06-24
• Study Start: 2013-07
• Primary Completion: 2016-01-31
• Study Completion: 2016-01-31
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-02
• Last Update Posted: 2018-10-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

AUDIT >7 for men and AUDIT >5 for women, and/or DUDIT >0

Exclusion Criteria

DUDIT = 0 and AUDIT <8 (men) or <6 (women)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in the total AUDIT-C score	3, 6 and 12 months	The primary outcome measure for this trial is the change in the total AUDIT score for the first three AUDIT questions, as a measure of alcohol consumption only, referred to as the AUDIT-C.

Secondary Outcome Measures

Name	Time	Method
Alcohol Use Disorders Identification Test (AUDIT)	3, 6 and 12 months	Change in total AUDIT score, as a summarized measure of alcohol use (including alcohol consumption and alcohol-related problems).

Trial Locations

Locations (1)

Karolinska institutet, Department of Clinical Neuroscience, Center for Psychiatric Research; 🇸🇪 Stockholm, Sweden