Predictors of Cardiac Troponin Release After Tour de Borobudur 2017
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 94
- 试验地点
- 1
- 主要终点
- Cardiac Troponin I (cTnI)
研究概览
简要总结
Prospective observational study to determine predictors that related to cardiac troponin I (cTnI) release, malondialdehyde (MDA) and high sensitivity C Reactive Protein (hs-CRP) after Tour de Borobudur (TdB) 2017
详细描述
Eligible Criteria:
- minimum sample size of 80 men, non-athlete, participants of TdB
- Classified into two groups: 160kms cycling and 100kms cycling participation
- 25-55 years old
- voluntary participate in the research
- eligible in pre participatory physical examination and ECG test by the doctor
- have no history of the previous acute coronary syndrome (ACS)
Measurements:
Interview for determining predictors of sports participation history, medical history, family medical history and Rate of Perceived Exertion Measurement and examination to determine: anthropometry parameters, clinical conditions (Systolic BP, Diastolic BP, hemoglobin levels, T-cholesterol and HDL-C levels, the intensity in cycling activities (mileage, velocity, duration, and time for resting), hemodynamic responses (average and maximum heart rate, Karvonen Index), and Hydration status
Other outcome measurements; pre and post-TdB 2017 measurements of cTnI, MDA, and hs-CRP
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •minimum sample size of 80 men, non athlete, participants of TdB
- •Classified into two groups: 160kms cycling and 100kms cycling participation
- •25-55 years old
- •voluntary participate in the research
- •eligible in pre participatory physical examination and ECG test by doctor have no history of previous acute coronary syndrome (ACS)
排除标准
- •stop cycling before finish line due to mechanical or bicycle related errors
- •(subjects who stop cycling due to any physical symptoms and health related problem included in analysis)
结局指标
主要结局
Cardiac Troponin I (cTnI)
时间窗: immediate after TdB 2017 cycling touring within less than 5 min
specific protein to determine cardiac injury
Malondialdehyde (MDA)
时间窗: immediate after TdB 2017 cycling touring within less than 5 min
oxydative stress marker
次要结局
- Number of Participants With Pathological ECG Appearance(immediate after TdB 2017 cycling touring within less than 5 min)
- High Sensitivity C Reactive Protein (Hs-CRP)(immediate after TdB 2017 cycling touring within less than 5 min)