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Moderna

Moderna logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
2010-01-01
Employees
5.6K
Market Cap
$30.3B
Website
http://www.modernatx.com
Introduction

Moderna, Inc. engages in the development of transformative medicines based on messenger ribonucleic acid (mRNA). Its product pipeline includes the following modalities: prophylactic vaccines, cancer vaccines, intratumoral immuno-oncology, localized regenerative therapeutics, systemic secreted therapeutics, and systemic intracellular therapeutics. The company was founded by Noubar B. Afeyan, Robert S. Langer, Jr., Derrick J. Rose and Kenneth R. Chien in 2010 and is headquartered in Cambridge, MA.

Clinical Trials

149

Active:48
Completed:67

Trial Phases

5 Phases

Phase 1:75
Phase 2:21
Phase 3:18
+2 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (121 trials with phase data)• Click on a phase to view related trials

Phase 1
75 (62.0%)
Phase 2
21 (17.4%)
Phase 3
18 (14.9%)
Not Applicable
3 (2.5%)
phase_1_2
2 (1.7%)
Phase 4
2 (1.7%)

A Study of mRNA-1345 Following a Primary Dose of a Licensed Protein Subunit Respiratory Syncytial Virus (RSV) Vaccine in Adult Participants ≥60 Years of Age

Not Applicable
Recruiting
Conditions
Respiratory Syncytial Virus
Interventions
First Posted Date
2025-08-12
Last Posted Date
2025-08-12
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
500
Registration Number
NCT07117487
Locations
🇺🇸

Velocity Clinical Research, Denver, Denver, Colorado, United States

🇺🇸

Indago Research & Health Center, Inc., Hialeah, Florida, United States

🇺🇸

Velocity Clinical Research, Savannah, Savannah, Georgia, United States

and more 8 locations

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

Not Applicable
Recruiting
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
Drug: mRNA-2808
First Posted Date
2025-08-11
Last Posted Date
2025-10-20
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
166
Registration Number
NCT07116616
Locations
🇺🇸

University of Alabama at Birmingham Hospital, Birmingham, Alabama, United States

🇺🇸

UCSF, San Francisco, California, United States

🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

and more 7 locations

A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Variant-containing Formulations

Not Applicable
Recruiting
Conditions
COVID-19
Interventions
Biological: mRNA-1283.251 Variant-containing Formulation
First Posted Date
2025-07-28
Last Posted Date
2025-10-14
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
832
Registration Number
NCT07089706
Locations
🇺🇸

DelRicht Research-Atlanta, Atlanta, Georgia, United States

🇺🇸

DelRicht Research-Baton Rouge, Baton Rouge, Louisiana, United States

🇺🇸

DelRicht Research-New Orleans, New Orleans, Louisiana, United States

and more 2 locations

A Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Solid Tumors

Phase 1
Not yet recruiting
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2025-03-17
Last Posted Date
2025-03-17
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
57
Registration Number
NCT06880536
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

🇺🇸

START San Antonio, San Antonio, Texas, United States

🇺🇸

START Mountain Region, West Valley City, Utah, United States

A Study of mRNA-4106 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Solid Tumors

Phase 1
Recruiting
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2025-03-17
Last Posted Date
2025-05-02
Lead Sponsor
ModernaTX, Inc.
Target Recruit Count
57
Registration Number
NCT06880549
Locations
🇺🇸

START Midwest, Grand Rapids, Michigan, United States

🇺🇸

START San Antonio, San Antonio, Texas, United States

🇺🇸

START Mountain Region, West Valley City, Utah, United States

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News

BIOVECTRA and Revolution Biomanufacturing Form Strategic Partnership for Integrated mRNA Development and Manufacturing

BIOVECTRA, part of Agilent Technologies, has partnered with Revolution Biomanufacturing to provide integrated mRNA sequence design and GMP manufacturing services.

Moderna Doses First Patient in Phase 1/2 Trial of Novel mRNA T-Cell Engager for Multiple Myeloma

Moderna has dosed the first patient with mRNA-2808, an investigational mRNA-based T-cell engager therapy for relapsed or refractory multiple myeloma, marking the company's first T-cell engager to reach clinical testing.

Moderna Shares Surge 12% on Reports of Potential Acquisition or Partnership Talks

Moderna stock jumped as much as 12% following reports that the company is in discussions with at least one large pharmaceutical company about a potential deal of significant scope.

4basebio's Synthetic DNA Platform Advances to Phase I/II Clinical Trials with Global Pharma Partner

4basebio PLC announces that a global Tier 1 pharmaceutical partner has begun dosing patients with an mRNA therapy developed using the company's proprietary opDNA® template following FDA IND approval.

Moderna's mRNA-1345 RSV Vaccine Shows Safety and Efficacy in Solid Organ Transplant Recipients

Moderna's mRNA-1345 RSV vaccine demonstrated safety and efficacy in a Phase III trial of 150 solid organ transplant recipients, with adverse events being mostly grade 1-2 and resolving within 2-3 days.

Moderna Discontinues CMV Vaccine Development After Phase 3 Trial Fails to Meet Primary Endpoint

Moderna's Phase 3 trial of mRNA-1647, an investigational cytomegalovirus vaccine, failed to meet its primary efficacy endpoint of preventing CMV infection in seronegative women aged 16-40.

Monash Scientists Decode RNA Splicing Mechanisms, Opening Path to Personalized mRNA Therapies

Monash University researchers have uncovered the genetic code governing how mutations affect RNA splicing, a critical cellular process for protein production.

Moderna's mRNA Flu Vaccines Show Promising Efficacy and Safety Data at IDWeek 2025

Moderna's seasonal flu vaccine mRNA-1010 demonstrated 26.6% relative vaccine efficacy compared to standard vaccines in adults aged 50 and above, meeting prespecified superiority criteria.

mRNA COVID-19 Vaccines Show Promise in Enhancing Cancer Immunotherapy Survival Rates

A new study reveals that mRNA COVID-19 vaccines from Pfizer/BioNTech and Moderna nearly double survival rates for lung cancer patients receiving immunotherapies.

Moderna Advances mRNA-4359 as Late-Stage Oncology Asset with New Melanoma Data

Moderna presented new data on mRNA-4359, which is rapidly advancing to become one of the company's newest late-stage oncology assets.

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