Biomarkers in Pulmonary Hypertension Associated to Interstitial Lung Disease

Completed

• Conditions: Interstitial Lung Disease; Pulmonary Hypertension; Biomarkers

• Registration Number: NCT00820729
• Lead Sponsor: University of Aarhus

Brief Summary

The presence of an abnormally increased pulmonary blood pressure worsens the prognosis of patients with interstitial pulmonary disease.

The aim of this study is to estimate the frequency of an increased blood pressure in the lungs among patient with interstitial pulmonary disease, and to evaluate the use of different biomarkers in diagnosis of the condition.

Detailed Description

The presence of increased pulmonary blood pressure is established by echocardiography and confirmed by right heart catheterization.

The ability of NT-proBNP, vWf, troponin-t, D-dimer and exhaled NO to predict the presence of increased pressure in the pulmonary circulation is evaluated.

Study Timeline

• Study First Submitted: 2009-01-09
• Study First Submitted QC: 2009-01-09
• Study First Posted: 2009-01-12
• Study Start: 2009-03
• Primary Completion: 2011-03
• Study Completion: 2011-03
• Status Verified: 2012-09
• Last Update Submitted: 2012-09-17
• Last Update Posted: 2012-09-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 212

Inclusion Criteria

• Interstitial pulmonary disease

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (2)

Department of Cardiology, Skejby sygehus; 🇩🇰 Århus N, Denmark

Department of Pulmonary Diseases, Århus Sygehus; 🇩🇰 Århus, Denmark