MedPath

The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human

Recruiting
Conditions
Coronary Heart Disease, Susceptibility to, 1
Interventions
Other: No intervention
Registration Number
NCT05945394
Lead Sponsor
Nanjing Medical University
Brief Summary

To evaluate the association of surem TRAF3IP2 levels with the atherosclerotic plaque development in human

Detailed Description

Previous study had concluded that TRAF3IP2 plays a causal role in atherosclerotic plaque development and vulnerability in mice. However, no human data was available. In the present study, patients who receive coronary angiography will be enrolled. Their surem TRAF3IP2 levels will be tested using ELASA. The association of surem TRAF3IP2 levels with the atherosclerotic plaque will be evaluated.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
800
Inclusion Criteria
  1. Patients with suspected coronary heart disease
  2. patients received coronary angiography
Exclusion Criteria
  1. NYHA III-IV
  2. malignant tumor
  3. acute infection
  4. thyroid dysfunction

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients with suspected CHD who experienced CAGNo interventionPatients with suspected coronary heart disease who experienced coronary angiography
Primary Outcome Measures
NameTimeMethod
stenosis of coronary artery1 week

The stenosis of coronary artery based on the results of coronary angiography

Secondary Outcome Measures
NameTimeMethod
coronary artery calcium1 week

The coronary artery calcification based on the results of coronary angiography

Trial Locations

Locations (1)

Huai'an First People's Hospital

🇨🇳

Huai'an, Jiangsu, China

© Copyright 2025. All Rights Reserved by MedPath