Prognostic Value of Surem TRAF3IP2 Level in Patients With Acute Myocardial Infarction

Recruiting

• Conditions: Myocardial Infarction, Acute

• Registration Number: NCT06038994
• Lead Sponsor: Nanjing Medical University

Brief Summary

To evaluate the prognostic value of surem TRAF3IP2 levels in patients with acute myocardial infarction

Detailed Description

Previous study had concluded that TRAF3IP2 plays a causal role in atherosclerotic plaque development and vulnerability in mice. However, no human data was available. In the present study, patients diagnosed with acute myocardial infarction who receive coronary angiography will be enrolled. Their surem TRAF3IP2 levels will be tested using ELASA. The association of surem TRAF3IP2 levels with the major adverse cardiac events will be evaluated.

Study Timeline

• Status Verified: 2023-09
• Study Start: 2023-09-01
• Study First Submitted: 2023-09-07
• Study First Submitted QC: 2023-09-08
• Last Update Submitted: 2023-09-08
• Study First Posted: 2023-09-15
• Last Update Posted: 2023-09-15
• Primary Completion: 2024-04-30
• Study Completion: 2025-04-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Patients with acute myocardial infarction
2. patients received coronary angiography
3. invasive management within 72 h of hospital admission

Exclusion Criteria

1. NYHA III-IV
2. malignant tumor
3. acute infection
4. thyroid dysfunction
5. Life expectancy of b1 y
6. Unsuitable for PCI

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MACEs (major adverse cardiac events)	1 year	MACEs were defined as a composite of cardiac death, hospitalization for myocardial infarction or heart failure

Secondary Outcome Measures

Name	Time	Method
hospitalization for myocardial infarction or heart failure	1 year	hospitalization for myocardial infarction or heart failure
cardiac death	1 year	and death due to cardiac reasons, such as myocardial infarction or heart failure

Trial Locations

Locations (1)

Huai'an First People's Hospital; 🇨🇳 Huai'an, Jiangsu, China