Prognostic Relevance of High-sensitivity Troponin in Patients With Acute Decompensated Heart Failure

Completed

• Conditions: Heart Failure

• Registration Number: NCT01429857
• Lead Sponsor: University Hospital, Saarland

Brief Summary

The purpose of this study is to investigate the prognostic value of admission high-sensitivity troponin in patients with acute decompensated heart failure.

Detailed Description

Patients admitted for acute decompensated heart failure are included in the study. After gaining informed consent, concentrations of high-sensitivity troponin on admission and on discharge are assessed. 6 months after discharged, the incidence of clinical endpoint (mortality of all cause and of cardiovascular cause, hospitalization) is assessed by telephone contact to the patient and/or the physician. The aim of the study is to investigate the prognostic value of high-sensitivity troponin concentration for predicting death and re-hospitalization.

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2011-02-01
• Study First Submitted QC: 2011-09-05
• Study First Posted: 2011-09-07
• Primary Completion: 2012-01
• Study Completion: 2012-01
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-13
• Last Update Posted: 2013-06-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 304

Inclusion Criteria

• Hospital admission for acute cardiac decompensation
• Systolic and / or diastolic heart failure

Exclusion Criteria

• Myocardial infarction in the last 4 weeks
• Serum creatinine >2.5 mg/dl
• Pulmonary embolism

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to cardiovascular death or hospitalization	6 Months Follow-Up

Secondary Outcome Measures

Name	Time	Method
Time to all cause death or hospitalization	6 Months Follow-Up

Trial Locations

Locations (1)

Innere Medizin III - Kardiologie, Angiologie und Internistische Intensivtherapie; 🇩🇪 Homburg, Saarland, Germany