PEWS Implementation in an LMIC Setting

Not Applicable

Completed

• Conditions: Oncology
• Interventions: Other: pediatric early warning scoring system and resuscitation curriculum

• Registration Number: NCT04180306
• Lead Sponsor: Boston Children's Hospital

Brief Summary

The PEWS implementation study will be undertaken with the following objectives:

1. Assess the effectiveness of implementation of PEWS and resuscitation training to identify patients at risk for clinical deterioration and to impact the frequency of clinical interventions made by treating providers on these patients.

2. Assess the effectiveness of implementation of PEWS and resuscitation training to impact time sensitive clinical interventions made on patients at risk for clinical deterioration.

3. Assess the impact of implementation of PEWS and resuscitation training on length of stay for patients admitted to the pediatric oncology ward.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-09-01
• Study First Submitted: 2019-11-23
• Study First Submitted QC: 2019-11-26
• Study First Posted: 2019-11-27
• Primary Completion: 2022-10-31
• Study Completion: 2023-09-30
• Status Verified: 2024-01
• Last Update Submitted: 2024-01-09
• Last Update Posted: 2024-01-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1850

Inclusion Criteria

• Patients eligible for the study are defined as pediatric patients (between birth and 12 years of age) admitted and subsequently discharged from the pediatric oncology ward in Beit Jala, Palestine and Gaza City, Palestine between March 2019 to June 2020

Exclusion Criteria

• Patients will be excluded if they are not admitted to inpatient status. No oncology outpatients such as those in the infusion program will be included.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Inpatient pediatric oncology patients	pediatric early warning scoring system and resuscitation curriculum	All patients admitted to the pediatric oncology ward will be in the cohort

Primary Outcome Measures

Name	Time	Method
Elevated Pediatric Early Warning Score (PEWS)	1 year	frequency of patients whose PEWS score indicates 'risk for clinical deterioration' and receive a clinical intervention. PEWS 3 or greater (Scale is PEWS 0-6) is defined as at risk for clinical deterioration with a higher score concerning for worse clinical outcome.

Secondary Outcome Measures

Name	Time	Method
Time to antibiotics	1 year	Time to antibiotics defined as time from documented vital signs/PEWS to time of antibiotic administration measured in minutes
Volume of IV fluids	1 year	Volume of fluids received defined as volume given up to 60 minutes after the initiation of the first fluid bolus measured in milliliters
Time to IV fluid bolus	1 year	Time to fluids defined as time from documented vital signs/PEWS to time of documented IV fluid bolus measured in minutes
Length of stay	1 year	Length of stay for all patients admitted to the inpatient ward

Trial Locations

Locations (2)

Rantisi Hospital; 🇵🇸 Gaza City, Palestinian Territory, occupied

Beit Jala Hospital; 🇵🇸 Bethlehem, Palestinian Territory, occupied