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Clinical Trials/NCT04734743
NCT04734743
Completed
N/A

Upper Extremity Muscle Strength and Endurance, Functional Capacity, Respiratory Function and Quality of Life in Child and Adolescent With Cystic Fibrosis

Cagtay Maden1 site in 1 country63 target enrollmentMay 1, 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cystic Fibrosis
Sponsor
Cagtay Maden
Enrollment
63
Locations
1
Primary Endpoint
Forced Expiratory Volume in 1 Second (FEV1)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This study was designed to investigate the relationship between upper extremity muscle strength and endurance, functional capacity, and quality of life child and adolescent with cystic fibrosis

Detailed Description

Child and adolescent with cystic fibrosis patients were assessed for upper extremity muscle strength and (Shoulder abductors muscle strength, Elbow flexion muscle strength, Handgrip strength) muscular endurance(arm pull-up test), lung function test, and functional capacity (six-minute walk test distance), and Quality Of Life (Cystic Fibrosis Questionnaire-Revised)

Registry
clinicaltrials.gov
Start Date
May 1, 2016
End Date
November 15, 2016
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Cagtay Maden
Responsible Party
Sponsor Investigator
Principal Investigator

Cagtay Maden

Principal Investigator, physiotherapist

Hasan Kalyoncu University

Eligibility Criteria

Inclusion Criteria

  • Individuals diagnosed with CF with clinical findings and gene mutations consistent with CF, having over 60mEq / L in two measurements in sweat chlorine examinations

Exclusion Criteria

  • Patients who did not exacerbate the disease in the last four weeks, who had good cooperation and did not have any orthopedic problems in the hand-shoulder-arm complex were included.

Outcomes

Primary Outcomes

Forced Expiratory Volume in 1 Second (FEV1)

Time Frame: 1 day

Pulmonary function tests were evaluated with a spirometer. It is the volume of air released in the first second from the beginning of the difficult vital capacity maneuver. In general, it gives information about the restriction in major airlines. FEV1 / FVC ratio decrease shows obstruction, FEV1 shows the severity of obstruction.

Upper Limb Muscle Strength

Time Frame: 1 day

Evaluation of peripheral muscle strength Deltoideus (shoulder abduction), Biceps Brachii (elbow flexion) muscles were evaluated with a digital dynamometer (Lafeyette manual muscle tester, U.S.A). Handgrip strength was measured by a hand dynamometer (Baseline LITE hand dynamometer, U.S.A). In each muscle test, the right and left sides were evaluated separately and repeated three times and the best values obtained were recorded in Newton (N). Arithmetic means of the right and left sides were used for statistical analysis.

Forced Vital Capacity (FVC)

Time Frame: 1 day

Pulmonary function tests were evaluated with a spirometer. It is the volume of air that comes out with rapid and powerful exhalation following deep inspiratory. Healthy people can normally extract 80 percent of their lung volume in 6 seconds or less

Ouality of Life

Time Frame: 1 day

Cystic Fibrosis Questionnaire-Revised (CFQ-R) was used to evaluate the quality of life. There are four CFQ-R questionnaires for parents of children aged 6 years and over, three different age groups \[6-10, 12-13, and over). The child's version of CFQ-R consists of 35 questions in 8 parts, Physical Functioning, Emotional Functioning, Social Functioning, Body Image, Eating Disturbances, Treatment Burden, Respiratory symptoms, and Digestive symptoms. Its values range from 0 to 100 points and the higher the score, the better quality of life.

Six-minute walk test

Time Frame: 1 day

In the 6-minute walk test (6MWT), subjects were asked to walk as fast as they could walk within 6 minutes along a 30-meter straight corridor. The test was performed twice within the same day at intervals of half an hour. The longer distance value for each patient from the two tests used was used for statistical analysis.

Peak Expiratory Flow (PEF)

Time Frame: 1 day

Pulmonary function tests were evaluated with a spirometer. It is measured by the maximum exhalation maneuver following the maximum inspiration. It gives information about obstruction in large airways.

Upper Limb muscular endurance

Time Frame: 1 day

The arm pull-up test was used in the evaluation of muscular endurance.

Study Sites (1)

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