JPRN-jRCTc030190081招募中1 期
Treatment with chemotherapy and dendritic cells pulsed with neoantigen-specific epitopes for pancreatic cancer. - PK-neoantigen-DCtest
Koido Shigeo0 个研究点目标入组 10 人开始时间: 2019年8月23日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 75age old（—）
- 性别
- All
入选标准
- •Human leukocyte antigen (HLA)-A*02:01- or A*24:02-positive patients.
- •Patients with histologically or cytologically confirmed locally advanced or metastatic pancreatic cancer, or recurrent disease after surgery.
- •Patients with ages between 20 and 75 years.
- •Karnofsky performance status (KPS) of 80% to 100%.
- •Patients with a KPS of 70% were also included but only if KPS was decreased by poorly controlled cancerous pain at enrollment.
- •Patients had adequate hematologic, hepatic, and renal function.
- •Patients had a life expectancy of at least 3 months.
- •All patients provided written informed consent.
排除标准
- •The exclusion criteria were pregnancy, serious infections, severe underlying disease, severe allergic disease, and a judgment of unsuitability by the principal investigator.
研究者
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