Smartphone based Monitoring and cognition Modification Against Recurrence of Depression - SMARD

Radboud Universitair Medisch Centrum0 个研究点目标入组 224 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

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•In order to be eligible to participate in this study, a patient must meet all of the following criteria:
•- recurrent MDD diagnoses (assessed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) (SCID) [First 1996])
•- at least 3 previous MDD-episodes (as assessed with the SCID-interview)
•- a 17-item Hamilton Depression Rating Scale (HDRS17) <=10 [Hamilton 1967], not fulfilling the criteria for a current MDD episode (as assessed with the SCID-interview)
•- having a stable remission (>=8 weeks)
•- age 18-65 years
•- in possession of smartphone and experienced in use thereof
•For the focus-groups in WP1, assessment of unipolarity, number of recurrences and non-depressed state will be assessed by history only (no SCID/HDRS17) as more thorough assessments are not proportional to the aim of the focus-groups.

•For both WPs:
•- diagnosis of bipolar, primary psychotic or borderline personality disorder or strong suspicion of this type of disorder
•- primary diagnosis of substance use or anxiety disorder with secondary MDD (comorbid secondary anxiety disorder allowed for participation)
•- electroconvulsive therapy within two months before inclusion
•- average alcohol intake of >3 units/day
•- daily use of benzodiazepines (>=5mg diazepam or equivalent)
•- Incompatible smartphone to install BeHapp ;Additional exclusion-criteria for WP2:
•- ongoing psychotherapy during the CCT/ABM training
•- previous CCT/ABM ;For the add-on MRI-part of WP2, standard MRI exclusion criteria will apply:
•- Metal objects in the body
•- Claustrophobia
•- A history of head trauma or neurological disease, severe general physical illness

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