NL-OMON20417招募中不适用
evothyroxine for euthyroid women with recurrent miscarriage and positive TPO antibodies: A randomized controlled trial.
Academic Medical Centre0 个研究点目标入组 240 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 240
研究概览
简要总结
/A
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Women with RM and thyroid autoimmunity. Recurrent miscarriage is defined as two or more miscarriages. TPOAb positivity is defined as euthyroid with presence of TPO antibodies. This will be defined according to the cut off levels of the coordinating or cooperating centres. Most commonly used are cut off levels from 60 kU/l or 100kU/l;
- •2. Age 18 - 42 years at randomisation;
排除标准
- •1. Antiphospholipid syndrome (lupus anticoagulant and/ or anticardiolipin antibodies IgG or IgM);
- •2. Other auto-immune conditions, diabetes mellitus, diabetes gravidarum, thyroid disease different then isolated thyroid autoimmunity;
研究者
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evothyroxine for recurrent miscarriageThyroid autoimmunity is associated with recurrent miscarriage and preterm birth. Thyroid autoimmunity means there is a normal thyroid function, but presence of thyroid antibodies, thyroid peroxidase antibodies (TPO-Ab).EUCTR2011-001820-39-NLAcademic medical centre240
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evothyroxine for recurrent miscarriageThyroid autoimmunity is associated with recurrent miscarriage and preterm birth. Thyroid autoimmunity means there is a normal thyroid function, but presence of thyroid antibodies, thyroid peroxidase antibodies (TPO-Ab).MedDRA version: 16.0Level: LLTClassification code 10027649Term: MiscarriageSystem Organ Class: 100000004868MedDRA version: 16.0Level: LLTClassification code 10027650Term: Miscarriage of pregnancySystem Organ Class: 100000004868MedDRA version: 16.0Level: LLTClassification code 10048437Term: Anti-thyroid antibodiesSystem Organ Class: 100000004848EUCTR2011-001820-39-DKAcademic medical centre240
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3 期
evothyroxine for euthyroid women with recurrent miscarriage and positive TPO antibodies: a randomized controlled trialNL-OMON44997Academisch Medisch Centrum160
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