EUCTR2011-001820-39-DK进行中（未招募）不适用
evothyroxine for euthyroid women with recurrent miscarriage and thyroid autoimmunity : a randomized controlled trial - T4Life
Academic medical centre0 个研究点目标入组 240 人开始时间: 2013年8月15日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 240
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- Female
入选标准
- •1.Women with unexplained RM and thyroid autoimmunity. Recurrent miscarriage is defined as two or more miscarriages. TPOAb positivity is defined as a TPO titre higher then 100 kU/ltr or two times higher then 60 kU/ltr.
- •2.Age 18 - 42 years at randomisation
- •3.Willing and able to give informed consent (IC).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 240
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1.Antiphospholipid syndrome (lupus anticoagulant and/ or anticardiolipin antibodies [IgG or IgM])
- •2. Other auto-immune conditions
- •3.Previous enrolment in the trial
- •4. Abnormal TSH levels
- •5. Contraindications to levothyroxine use:
- •Adrenal or pituitary disorders, untreated
- •Thyreotoxicosis, untreated
- •Acute cardiac arrest
- •Acute pancreatitis
- •Acute myocarditis
研究者
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