Effect of phytosomal curcumin supplementation on patients with migraine

Phase 3

• Conditions: Post-traumatic headache.; Chronic post-traumatic headache; G44.3

• Registration Number: IRCT20201129049534N2
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients who agree to participate in the study and complete the informed consent form.
Diagnosis of migraine headache by a neurologist using the third edition of the International Headache Disorders Questionnaire.
Age: 18 to 80 years old

Exclusion Criteria

Taking anticoagulants such as warfarin, heparin, aspirin, etc.
Pregnancy and lactation
Follow a special diet in the last 3 months
Use of herbal supplements in the last 3 months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of migraine headache. Timepoint: At baseline and end of the study. Method of measurement: VAS scale.;Frequency of migraine headache. Timepoint: At baseline and end of the study. Method of measurement: Number of migraine headache attacks per month.;Duration of migraine headache. Timepoint: At baseline and end of the study. Method of measurement: The average duration of migraine headache attacks per hour per headache.;Nitric oxide. Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;Total antioxidant capacity. Timepoint: At baseline and end of the study. Method of measurement: ELISA test.;C-Reactive Protein – CRP. Timepoint: At baseline and end of the study. Method of measurement: ELISA test.

Secondary Outcome Measures

Name	Time	Method
Quality of Life. Timepoint: At baseline and end of the study. Method of measurement: Quality of life questionnaire.