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Electrical Muscle Stimulation on Muscle Mass, Strength, and Body Composition

Not Applicable
Completed
Conditions
Resistance Training
Electrical Muscle Stimulation
Exercise
Interventions
Device: electrical muscle stimulation
Registration Number
NCT06036953
Lead Sponsor
National Taiwan Sport University
Brief Summary

In recent years, electrical muscle stimulation (EMS) devices have been developed as a complementary training technique that is novel, attractive, and time-saving for physical fitness and rehabilitation. While it is known that EMS training can improve muscle mass and strength, most studies have focused on the elderly or specific patient populations. The aim of this study was to investigate the effects of frequency-specific EMS combined with resistance exercise training for 8 weeks on muscle mass, strength, power, body composition, and parameters related to exercise fatigue. Additionally, we aimed to evaluate the feasibility and safety of EMS as an exercise aid to improve body composition. We recruited 14 male and 14 female subjects who were randomly assigned to two groups with gender parity (7 male and 7 female/group): (1) no EMS group and (2) daily EMS group. Blood biochemical routine analysis was performed every 4 weeks from pre-intervention to post-intervention, and body composition, muscle strength, and explosive power were evaluated 8 weeks before and after the intervention. We also performed an exercise challenge analysis of fatigue biochemical indicators after 8 weeks of intervention.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
28
Inclusion Criteria
  • healthy
Exclusion Criteria
  • smoking or drinking habits
  • cardiovascular disease
  • neuromuscular disease
  • metabolic disease
  • asthma
  • pregnancy
  • body mass index (BMI) over 27

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
EMSelectrical muscle stimulation-
Primary Outcome Measures
NameTimeMethod
The Countermovement Jump (CMJ) Testup to 8 weeks

The CMJ test is a practical, effective, reliable, and simple method of measuring lower limb strength, which is related to the maximum speed, strength and explosive force of the lower limbs. For this test, participants stood on the Kistler force measurement platform (9260AA, Kistler Co., Ltd., Switzerland) on both feet and performed to inspection. During the test, they were asked to put their hands on their hips and remain on the platform. After that, they were asked to squat down until the knees bent 90 degrees and then to immediately jump as high as possible. The average power (MF), were recorded during the jump. Each participant repeated the test 3 times, and CMJ data were obtained at the designated points. The instrument was calibrated for each individual's weight.

Clinical Biochemistry of glucose levelAfter 8 weeks of EMS

For assessment of fatigue-related indices, volunteers fasted for at least 8 h before the 60% VO2max fixed intensity exercise challenge. Blood samples were collected with an arm venous catheter at indicated time points during exercise and recovery periods, including baseline (0), 30 (E30) min during the exercise phase, and 60 (R60) min in the recovery phase. Serum glucose (mg/dL), were assessed for monitoring physiological adaptation. All biochemical indices were assessed using an autoanalyzer (Hitachi 7060, Tokyo, Japan).

VO2maxAfter 8 weeks of EMS

To evaluate the maximum oxygen consumption and exercise performance, we used a treadmill (Pulsar, h/p/cosmos, Nussdorf-Traunstein, Germany) and an automatic breathing analyzer (Vmax 29c, Sensor Medics, Yorba Linda, CA, USA). In addition, a polar heart rate device was used to monitor the heart rate (HR). The speed range of the treadmill was set to 7.2 km/h and increased by 1.8 km/h every 2 min until fatigue, according to Bruce's protocol. When the breathing exchange rate (the volume ratio of carbon dioxide produced to oxygen consumed, VCO2/VO2) was higher than 1.10 and reached the maximum heart rate (maximum heart rate = 220 - age), oxygen consumption was considered to be maximum. The three highest VO2max peak were averaged to obtain the VO2max values of the individual volunteers.

Body composition_body fatup to 8 weeks

The multi-frequency principle was applied to measure body composition by using a bioelectrical impedance analyzer (BIA) on an InBody 570 device (In-body, Seoul, South Korea). To perform the measurements, after the subjects' palms and soles were removed from the sensors, the subjects stood on the footing electrodes and held the sensing handles with two hands. During the measurements, the subjects kept their arms open and left their bodies at an angle of 30° without speaking or moving. The subjects also fasted for at least 8 h before the test. The body fat were meansure

Grip strengthup to 8 weeks

Use the armed grip machine (T.K.K.5401, Takei Scientific Instruments Co.,Ltd, Niigata, Japan) to measure, hold each of the left and right hands three times until they are weak, and record the maximum value

Clinical Biochemistry of ammonia levelAfter 8 weeks of EMS

For assessment of fatigue-related indices, volunteers fasted for at least 8 h before the 60% VO2max fixed intensity exercise challenge. Blood samples were collected with an arm venous catheter at indicated time points during exercise and recovery periods, including baseline (0), 30 (E30) min during the exercise phase, and 60 (R60) min in the recovery phase. Serum ammonia (umol/L), were assessed for monitoring physiological adaptation. All biochemical indices were assessed using an autoanalyzer (Hitachi 7060, Tokyo, Japan).

Body composition_muscle massup to 8 weeks

The multi-frequency principle was applied to measure body composition by using a bioelectrical impedance analyzer (BIA) on an InBody 570 device (In-body, Seoul, South Korea). To perform the measurements, after the subjects' palms and soles were removed from the sensors, the subjects stood on the footing electrodes and held the sensing handles with two hands. During the measurements, the subjects kept their arms open and left their bodies at an angle of 30° without speaking or moving. The subjects also fasted for at least 8 h before the test. The muscle mass were meansure

Clinical Biochemistry of lactate levelAfter 8 weeks of EMS

For assessment of fatigue-related indices, volunteers fasted for at least 8 h before the 60% VO2max fixed intensity exercise challenge. Blood samples were collected with an arm venous catheter at indicated time points during exercise and recovery periods, including baseline (0), 30 (E30) min during the exercise phase, and 60 (R60) min in the recovery phase. Serum lactate (mmol/L), were assessed for monitoring physiological adaptation. All biochemical indices were assessed using an autoanalyzer (Hitachi 7060, Tokyo, Japan).

Secondary Outcome Measures
NameTimeMethod
Safety assessment - ALTbaseline, 4 week and 8 week

Safety is assessed function of liver such as ALT (4-44 IU/L).

Safety assessment - Uric Acidbaseline, 4 week and 8 week

Safety is assessed function of kidney such as Uric Acid (3.4-7.6 mg/dl)

Safety assessment - BUNbaseline, 4 week and 8 week

Safety is assessed function of kidney such as Bun (6-20 mg/dl)

Safety assessment - total proteinbaseline, 4 week and 8 week

Safety is assessed function of kidney such as total protein (6.4-8.9 g/dl)

Safety assessment - ASTbaseline, 4 week and 8 week

Safety is assessed function of liver such as AST (8-38 IU/L).

Safety assessment - Creatininebaseline, 4 week and 8 week

Safety is assessed function of kidney such as Creatinine (0.6-1.3 mg/dl)

Safety assessment - free fatty acidbaseline, 4 week and 8 week

Safety is assessed function of lipid metabolism such as free fatty acid (0.1-0.9 mmol/L)

Trial Locations

Locations (1)

Graduate Institute of Sports Science, National Taiwan Sport University

🇨🇳

Taoyuan, Taiwan

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