To compare the effects of standard vs transpulmonary pressure guided intraoperative PEEP on post operative pulmonary complications in patients undergoing upper abdominal surgeries

All India Institute of Medical Sciences0 个研究点目标入组 200 人开始时间: 待定最近更新: 2024年7月22日

试验速览

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•1.Patients of ASA Physical Status I – III scheduled for elective upper abdominal surgery with expected duration of surgery more than 1 hour under general anaesthesia.
•2.BMI between 18 and 35 kg/m2.
•3.Age more than 18 years.

•1.Patient refusal
•2.Emergency surgeries
•3.Previous history of any thoracic surgeries
•4.Pregnancy
•5.Any nasopharyngeal or oropharyngeal pathologies
•6.Contraindications to nasogastric tube placement.
•7.Any laparoscopic surgeries being converted to open surgeries.
•8.Chronic Obstructive Pulmonary Disease, Bronchial Asthma or other chronic lung diseases
•9.Deformity of chest wall or thoracic spine
•10.preoperative diagnosis of pneumonia
•11.BMI <18 kg/m2 or > 35 kg/m2
•12.Significant cardiac, renal or hepatic diseases
•13.Intraoperative massive blood loss (blood loss >40ml/kg) or massive transfusion ( >8 PRBC transfusion during surgery)
•14.Patients on high dose vasopressor (noradrenaline > 10mcg/min or equivalent)

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