COMPARATIVE EVALUATION OF TRANSPULMONARY PRESSURE GUIDED VENTILATION VERSUS CONVENTIONAL VENTILATION IN PATIENTS WITH A.R.D.S

self0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•Patients will be included in the study if they have moderate-to-severe ARDS according to the American-European Consensus Conference definitions.
•Duration of ARDS 36 hours or less from meeting final Berlin criterion
•Age more than 18 years.

•Received mechanical ventilation more than 96â??h.
•Recently treated for bleeding varices, stricture, haematemesis, esophageal trauma, recent esophageal surgery or other contraindication for nasogastric tube placement.
•History of lung or liver transplantation.
•Severe chronic liver disease (Child-Pugh Score >=12).
•Patients not committed to full support.
•Inability to get informed consent from the patient or surrogate.
•Use of rescue therapies prior to enrolment (including nitric oxide, ECMO, prone positioning)
•Evidence of active air leak from the lung (including bronchopleural fistula, pneumothorax, pneumomediastinum or air leak from existing chest tube).

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