The Effect of a Personalised Training Programme on the Functional Ability and the Quality of Life of Candidates for Liver Transplantation
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Change from Baseline "Liver Frailty Index" value at 12 weeks
研究概览
简要总结
The aim of the study is to investigate the effect of personalised exercise interventions in liver transplant candidates, aiming to prevent or limit sarcopenia and frailty, as well as improving their cardiorespiratory health.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Liver transplant candidates, accepted in the waiting list of the Surgical Department of Transplantation A.U.Th., General Hospital of Thessaloniki "Ippokratio".
排除标准
- •Recent (<12 months) Acute Myocardial Infraction
- •Recent (<12 months) brain strokes
- •Uncontrolled and/or untreated arrythmia
- •Hepatic encephalopathy
- •Bed-bound patient
- •Liver Transplantation
研究组 & 干预措施
Regular treatment
Exercise Intervention
干预措施: Personalised exercise (Behavioral)
结局指标
主要结局
Change from Baseline "Liver Frailty Index" value at 12 weeks
时间窗: After 12-week exercise intervention
A frailty index for patients with cirrhosis, comprised of three performance-based metrics
Change from Baseline "6 Minute Walking Test" value at 12 weeks
时间窗: After 12-week exercise intervention
A walking test for patients to evaluate their functional capacity
次要结局
- VO2max(Before intervention initiation and after 12-week exercise intervention)
研究者
Ilias Marios Oikonomou
Scientific Associate for the Surgical Department of Transplantation A.U.Th., Postgraduate Student, Medical Doctor
Aristotle University Of Thessaloniki