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Role of Stem Cells and Platelet Rich Plasma in regenerating uterine lining (endometrium) in women with uterine adhesions and thin endometrium

Phase 2
Conditions
Health Condition 1: N972- Female infertility of uterine origin
Registration Number
CTRI/2024/02/062437
Lead Sponsor
INDIAN COUNCIL FOR MEDICAL RESEARCH ICMR
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Women with Asherman’s syndrome that have undergone hysteroscopic adhesiolysis resulting in

Normal/optimal cavity size yet atrophic endometrium ( <5 mm) on ultrasound despite standard estrogen therapy

2. Women with refractory atrophic endometrium ( <5 mm endometrial thickness on ultrasound) despite standard estrogen therapy

3. Willing to participate in the study

Exclusion Criteria

1. Women with Asherman’s syndrome after surgical correction with suboptimal uterine cavity

2. Genital tuberculosis (the disease has profound effects on compromising cavity size, compromising sub-endometrial vascularity and being a pilot work will be selective on cases)

3. Hematologic disorders, hemoglobin level of <11.0 g/dL or platelet count of <150,000/µl

4. Chronic autoimmune diseases

5. Refusal to participate in study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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