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Ranibizumab Versus Dexamethasone Implant in Diabetic Macular Edema

Completed
Conditions
Diabetic Macular Edema
Interventions
Registration Number
NCT03385382
Lead Sponsor
G. d'Annunzio University
Brief Summary

Between December 2016 and June 2017 a total of 40 eyes from 40 diabetic retinopathy patients with diabetic macular edema were recruited at the Ophthalmologic Clinic of University "G. d'Annunzio", Chieti-Pescara, Italy.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Age >18 years old
  • BCVA greater than 0.5 LogMAR in the study eye at baseline examination
  • Presence of recent DME
  • CMT > 300µm as measured using the SD-OCT at the baseline examination
Exclusion Criteria
  • Any previous ocular surgery in the last 6 months
  • Laser treatments
  • Prior ocular trauma
  • Retinal vascular diseases
  • Vitreo-retinal interface diseases
  • Medium lens opacities (according to Lens Opacities Classification System)

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
ranibizumabRanibizumab InjectionPatients with diabetic macular edema receiving ranibizumab
Dexamethasone groupDexamethasone intravitreal implant 0.7 mgPatients with diabetic macular edema receiving dexamethasone
Primary Outcome Measures
NameTimeMethod
Central macular thickness6 months

Decrease of macular thickness

Secondary Outcome Measures
NameTimeMethod
visual acuity6 months

Increase of mean visual acuity

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