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Statins to Prevent Rheumatoid Arthritis (STAPRA)

Conditions
Rheumatoid arthritis, RA, Arthralgia, Atorvastatin, seropositive, ACPA, RF, preventionreumatoide arthritis, artralgie, atorvastatine, seropositief, preventie
Registration Number
NL-OMON19910
Lead Sponsor
Amsterdam Rheumatology & immunology Center | Reade
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
220
Inclusion Criteria

1) Age >= 18 years

2) Seropositive

Exclusion Criteria

1) Patients with synovitis during clinical examination (any of 44 joints of DAS) at inclusion or synovitis in the past during clinical examination by a rheumatologist.

2) Patients with typical RA erosions on X-rays of hand and feet.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The occurrence of clinical arthritis confirmed by a rheumatologist participating in the study.
Secondary Outcome Measures
NameTimeMethod
Effect on improvement of lipid profile, (sub)clinical CV risk, inflammatory parameters and changes in cIMT and arterial stiffness.
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